Detection of Human Papillomavirus DNA by In Situ Hybridization Using Biotinylated DNA Probes in Codylomata Acuminata.
- Author:
Seok Ju KIM
;
Kyu Suk LEE
;
Joon Young SONG
;
Seong Il SUH
;
Min Ho SUH
- Publication Type:Original Article
- Keywords:
Condylomata accuminata;
HPV;
In situ hyb;
Idization
- MeSH:
DNA Probes*;
DNA*;
Humans*;
In Situ Hybridization*;
Vagina;
Vulva
- From:Korean Journal of Dermatology
1990;28(6):702-707
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Human Papillomaviruses(HPVs) are regarded as sexually transmitable and closely associated with precancerous lesions or invasive cancers of the vulva, vagina, and cer V1X. In situ hybridization, besides showing higher sensitivity, allowed the identification of specific viral types. We studied 12 cases of condylomata accuminata for HPV typing by in situ hybridization techenique. Ten cases(83.3 % ) showed positive for HPV type 6/11, and 2 cases(16.7% ) were positive for HPV type 16/18.