Turner syndrome with spinal hemorrhage due to vascular malformation.
10.6065/apem.2015.20.4.235
- Author:
Min Kyung YU
1
;
Mo Kyung JUNG
;
Ki Eun KIM
;
Ah Reum KWON
;
Hyun Wook CHAE
;
Duk Hee KIM
;
Ho Seong KIM
Author Information
1. Department of Pediatrics, Severance Children's Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul, Korea. hopechae@yuhs.ac
- Publication Type:Case Report
- Keywords:
Turner syndrome;
Vascular malformations;
Vertebral artery dissection
- MeSH:
Cardiovascular System;
Child;
Chromosome Disorders;
Comorbidity;
Dexamethasone;
Diagnosis;
Female;
Growth Hormone;
Hemorrhage*;
Humans;
Leg;
Lower Extremity;
Magnetic Resonance Imaging;
Rupture;
Spine;
Turner Syndrome*;
Vascular Malformations*;
Vertebral Artery;
Vertebral Artery Dissection
- From:Annals of Pediatric Endocrinology & Metabolism
2015;20(4):235-237
- CountryRepublic of Korea
- Language:English
-
Abstract:
Turner syndrome (TS) is a relatively common chromosomal disorder and is associated with a range of comorbidities involving the cardiovascular system. Vascular abnormalities, in particular, are a common finding in cases of TS. However, dissection involving the vertebral arteries is rare. Here, we report the case of a 9-year-old girl with TS who had been treated with growth hormone replacement therapy for the past 3 years. She presented with weakness of both lower legs, and was ultimately diagnosed with spinal hemorrhage due to vascular malformation. We treated her with intravenous high dose dexamethasone (0.6 mg/kg) and she could walk without assistance after 6 days of treatment. In conclusion, when a patient with TS shows sudden weakness of the lower limbs, we should consider the possibility of spinal vessel rupture and try to take spine magnetic resonance imaging as soon as possible. We suggest a direction how to make a proper diagnosis and management of sudden vertebral artery hemorrhage in patients with TS.
