A case of peripheral T-cell lymphoma presenting with a necrotizing gingival ulcer.
- Author:
Hong Sung CHOUGH
1
;
Yu Jin JEONG
;
Jung Yeon HAN
;
Hyun Sook KIM
Author Information
1. Department of Internal Medicine, College of Medicine, Chosun University School of Medicine, Gwangju, Korea. healthyra@chosun.ac.kr
- Publication Type:Case Report
- Keywords:
Peripheral T-cell lymphoma;
Gingival ulcer
- MeSH:
Adult;
Aged, 80 and over;
Biopsy;
Eosinophilia;
Europe;
Fever;
Humans;
Liver;
Lymphatic Diseases;
Lymphoma;
Lymphoma, Non-Hodgkin;
Lymphoma, T-Cell;
Lymphoma, T-Cell, Peripheral;
Pruritus;
Skin;
Spleen;
Ulcer;
United States;
Viscera
- From:Korean Journal of Medicine
2010;78(6):766-770
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Peripheral T-cell lymphoma (PTCL) is a heterogenous group of generally aggressive neoplasms constituting less than 15% of all non-Hodgkin's lymphomas in adults. PTCL unspecified (PTCL-U) comprises 6% of lymphomas in the United States and Europe. Most patients with PTCL-U present with generalized lymphadenopathy and hemophagocytosis, eosinophilia, and pruritus involving the skin, liver, spleen, and other viscera. Gingival and genital ulcers are a very uncommon manifestation. The diagnosis of PTCL-U is based on the results of a tissue biopsy that shows evidence of T-cell lymphoma that does not meet the criteria for other subtypes of T-cell lymphoma. Here, we describe an 85-year-old man with intermittent fever and necrotizing gingival and genital ulcers who was diagnosed with PTCL-U after a gingival biopsy.
