A Case of Hypertrophic Osteoarthropathy Associated with Nasopharyngeal Carcinoma in a Child.
10.3346/jkms.2003.18.5.761
- Author:
Seung Hyun SOHN
1
;
Seung Hoon RYU
;
Hyuk Chan KWON
;
Mi Kyoung PARK
;
Sung Won LEE
;
Won Tae CHUNG
Author Information
1. Department of Internal Medicine, College of Medicine, Dong-A University, Busan, Korea. comeinus@damc.or.kr
- Publication Type:Case Report
- Keywords:
Osteoarthropathy, Secondary Hypertrophic;
Nasopharyngeal Neoplasms
- MeSH:
Adolescent;
Bone and Bones/radiography;
Carcinoma/*diagnosis/mortality;
Disease Progression;
Fatal Outcome;
Human;
Joint Diseases/pathology;
Lung Neoplasms/mortality/*secondary;
Male;
Nasopharyngeal Neoplasms/*diagnosis/mortality;
Neoplasm Metastasis;
Osteoarthropathy, Primary Hypertrophic/*diagnosis/mortality/radiography;
Prognosis
- From:Journal of Korean Medical Science
2003;18(5):761-763
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hypertrophic osteoarthropathy is characterized by clubbing of the digital tips and periosteal reaction of long bones. Most of the cases are associated with malignancy or other conditions such as congenital heart disease, liver cirrhosis, pulmonary fibrosis, biliary atresia, and gastrointestinal polyps. Hypertrophic osteoarthropathy associated with malignancy is rare in children. A few cases of hypertrophic osteoarthropathy in children with nasopharyngeal carcinoma have been reported, however, there has been no report of such case in Korea. We present a case of hypertrophic osteoarthropathy associated with nasopharyngeal carcinoma with lung metastasis in a 14-yr-old boy. In this case, hypertrophic osteoarthropathy regressed after intensive chemotherapy, but subsequently the patient died of progressive lung metastasis.
