Cryptogenic Gelastic Seizures from Medial Frontal Area: 2 Cases.
- Author:
So Young MOON
1
;
Dae Won SEO
;
Hahn Young KIM
;
Seung Chul HONG
;
Seung Bong HONG
Author Information
1. Department of Neurology, Samsung Medical center, Sungkyunkwan University School of Medicine, Korea. dwseo@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Gelastic seizures;
Invasive EEG monitoring;
Medial frontal cortex
- MeSH:
Humans;
Laughter;
Seizures*
- From:Journal of the Korean Neurological Association
2002;20(6):716-720
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Little has been known about what pathways subserve mirth and its expression laughter. We report two patients with cryptogenic gelastic seizures who provide some insight into the mechanisms of laughter. Invasive video-EEG monitoring showed ictal onset zone to be either in the left or right medial frontal cortex. After resection of the medial frontal area, including the epileptogenic focus, patients have been in gelastic seizure-free state. This suggests the possibility that medial frontal cortex is involved in the motor act of laughter.
