A Typical Korean Case Of Carney Complex.
- Author:
Hyun Dae YOON
1
;
Ho Sang SHON
Author Information
1. Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea. hdyoon@cu.ac.kr
- Publication Type:Case Report
- Keywords:
Multiple primary neoplasms;
Adrenal cortex neoplasm;
Cushing syndrome
- MeSH:
Adult;
Cushing Syndrome/*diagnosis;
Female;
Human;
Hyperpigmentation/diagnosis;
Magnetic Resonance Imaging;
Multiple Endocrine Neoplasia/diagnosis;
Myxoma/*diagnosis/genetics;
Neoplasms, Multiple Primary/*diagnosis;
Pituitary Neoplasms/*diagnosis;
Skin Neoplasms/*diagnosis/genetics;
Syndrome
- From:The Korean Journal of Internal Medicine
2003;18(4):260-265
- CountryRepublic of Korea
- Language:English
-
Abstract:
Carney complex is a multiple neoplasia syndrome, inherited in an autosomal dominant manner, that is characterized by lentigines, cardiac myxoma, and numerous endocrine and other tumors, including primary pigmented nodular adrenocortical disease. Here, we describe a typical case of Carney complex in a 27- year-old female who exhibited spotty skin pigmentation on the lips, oral mucosa, fingers, and toes and several manifestations of Cushing's syndrome due to primary pigmented nodular adrenocortical disease. She also had pituitary adenoma, breast tumor and thyroid nodule. Only a few cases of this disorder have been reported in the Korean literature. All of them, however, had only two components of Carney complex: composed of skin pigmentation and primary pigmented nodular adrenocortical disease. Therefore, the present case seems to be the first true case of Carney complex reported in Korea.
