Recent Changes of Organism and Treatment in Pyogenic Liver Abscess.
- Author:
Byung Kyu NAH
1
;
Yeon Soo KIM
;
Hee Seok MOON
;
Ki Oh PARK
;
Sun Moon KIM
;
Yeum Seok LEE
;
Hyeon Woong YANG
;
Seung Weon SEO
;
Seok Hyun KIM
;
Byung Seok LEE
;
Nam Jae KIM
;
Heon Young LEE
Author Information
1. Department of Internal medicine, Chungnam National University College of medicine, Daejeon, Korea. leehy@hanbat.chungnam.ac.kr
- Publication Type:Original Article ; English Abstract
- Keywords:
Liver;
abscess;
pyogenic;
Klebsiella pneumoniae
- MeSH:
Adolescent;
Adult;
Child;
English Abstract;
Female;
Humans;
*Liver Abscess, Pyogenic/microbiology/pathology/therapy;
Male;
Middle Aged
- From:The Korean Journal of Hepatology
2003;9(4):275-283
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: With the advance of antibiotics and the development of newer imaging techniques, marked changes in etiology, diagnosis, treatment and prognosis of liver abscess have been reported. METHODS: We reviewed the clinical data related to 94 patients with pyogenic liver abscess. RESULTS: Of the 94 patients in the study group, the male to female ratio was 1.4:1 and the peak incidence of liver abcess was in the 7th decade. About three quaters (74.5%) of the abcesses were of unknown origin. The predominant location was in the right lobe (70.3%). Single lesion was found in 80 patients and multiple lesions in 14 patients. Pathogens were identified in 67 patients, of which Klebsiella pneumoniae (65.7%) and E. coli (16.4%) were the most common. The modalities of treatment were percutaneous drainage with antibiotics (73.4%), percutaneous aspiration with antibiotics (16.0%), or antibiotics alone (8.5%). The case fatality rate, mainly from associated underlying diseases, was 9 cases (9.6%). Associated diseases were diabetes mellitus (14.9%) and malignancy (10.6%). CONCLUSIONS: Our study revealed that the most common organism was Klebsiella pneumoniae and percutaneous needle aspiration and/or catheter drainage were safe and effective treatment modalities for pyogenic liver abscess. Prognosis was determined by the underlying condition.
