Valproic Acid-Induced Hyperammonemic Encephalopathy Initially Misdiagnosed as Nonconvulsive Status Epilepticus.
- Author:
Ji Ae KO
1
;
Il Kyo SEO
;
Ho Jeong PARK
;
Tae Kyeong LEE
;
Sun Ah PARK
;
Young Soon CHO
Author Information
1. Department of Neurology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea. sapark@schmc.ac.kr
- Publication Type:Case Report
- Keywords:
Electroencephalography (EEG);
Epilepsy;
Valproic acid
- MeSH:
Electroencephalography;
Epilepsy;
Humans;
Liver;
Status Epilepticus;
Valproic Acid
- From:Journal of the Korean Society of Emergency Medicine
2011;22(4):382-386
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Valproic acid-induced hyperammonemic encephalopathy (VHE) is a very rare but serious complication. Discontinuation of valproic acid is the first and critical step for treatment. VHE can occur in people with normal liver function, despite normal doses and serum levels of valproic acid, therefore it is very hard to predict. Recently, we experienced a case of VHE. Here we will present the clinical, laboratory and electroencephalography findings in this patient.
