The Detectability of Hepatic Metastases in Candidates of Radiofrequency Ablation: Comparison for Helical CT Scanning and Late-Phase Pulse-Inversion Harmonic Imaging.
10.3348/jkrs.2002.46.2.149
- Author:
Kang Won LEE
1
;
Kwon Ha YOON
;
Eun A KIM
;
Ki Han PARK
;
Seon Kwan JUHNG
;
Jong Jin WON
Author Information
1. Department of Radiology, Wonkwang University School of Medicine. yoonkh@wmc.wonkwang.ac.kr
- Publication Type:Original Article
- Keywords:
Liver, neoplasms;
Liver, CT;
Liver, US;
Ultrasound (US), contrast agents
- MeSH:
Catheter Ablation*;
Colorectal Neoplasms;
Contrast Media;
Humans;
Microbubbles;
Neoplasm Metastasis*;
Tomography, Spiral Computed*;
Tomography, X-Ray Computed
- From:Journal of the Korean Radiological Society
2002;46(2):149-154
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To compare dual-phase helical CT and pulse inversion harmonic US using microbubble contrast agents in the detection of hepatic metastases prior to radiofrequency (RF) ablation. MATERIALS AND METHODS: Twenty-one patients in whom hepatic metastases from colorectal cancer had been diagnosed by dual-phase CT scanning and who were considered to be candidates for RF ablation underwent pulse-inversion barmonic US examination. Images were obtained 5 minutes after the bolus injection of microbubble contrast agent SH U 508 A (4.0 g, 300 mg/mL). The number of metastatic tumors revealed by CT and US was determined, and the findings were statistically analysed. The influence of the results of US examination on treatment planning was also evaluated. RESULTS: In 21 patients, 48 metastatic lesions were detected by helical CT, and 56 lesions by US. These eight additional lesions revealed by US occurred in six patients (29%), and their diameter was 3-13 (mean, 7.2) mm. In three of these patients, RF ablation could not be performed, while in the other three, the additional lesions were ablated. CONCLUSION: Pulse-inversion harmonic US imaging using microbubble contrast agents may depict small hepatic metastatic tumors that were not apparent at CT. US-therefore appears to be useful in the planning of treatment prior to the RF ablation of hepatic metastases.
