Formula fed twin infants with recurrent hypocalcemic seizures with vitamin D deficient rickets and hyperphosphatemia.
10.6065/apem.2015.20.2.102
- Author:
Byung Wook JO
1
;
Ye Jee SHIM
;
Jin Hyeok CHOI
;
Jun Sik KIM
;
Hee Joung LEE
;
Heung Sik KIM
Author Information
1. Department of Pediatrics, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea. kimhs@dsmc.or.kr
- Publication Type:Case Report
- Keywords:
Twins;
Vitamin D deficiency;
Hypocalcemia;
Seizures;
Rickets
- MeSH:
Breast;
Calcium;
Eating;
Female;
Follow-Up Studies;
Humans;
Hyperphosphatemia*;
Hypocalcemia;
Infant*;
Infant, Low Birth Weight;
Infant, Newborn;
Phosphorus;
Pregnant Women;
Premature Birth;
Rickets*;
Seizures*;
Twins*;
Vitamin D Deficiency;
Vitamin D*
- From:Annals of Pediatric Endocrinology & Metabolism
2015;20(2):102-105
- CountryRepublic of Korea
- Language:English
-
Abstract:
Vitamin D deficient rickets is generally known to occur in breast fed infants. And excessive phosphate ingestion is a main cause of late onset hypocalcemia in formula fed infants. Here we introduce 45-day-old formula fed hypocalcemic twins with recurrent seizure attacks. They were diagnosed as having both of vitamin D deficient rickets and hyperphosphatemia. Radiologic findings indicated mild rickets and the twins were treated with calcium and alfacalcidol. After 3-5 months of oral supplementation, medication was discontinued in both twins. They showed normal growth and calcium, phosphorus, and vitamin D levels during the 6-month follow-up period. Twins can be at risk for hypocalcemia because of their high risk of vitamin D deficiency, low birth weight, and premature birth. Therefore twin pregnant women need ingestion of sufficient vitamin D and calcium.
