Radiation Treatment for Malignant Small Cell Tumor of the Thoracopulmonary RegionPrimitive Pluripotent Histogenesis and Differential Diagnosis: A Case Report and Review of Literatures.
- Author:
Won Young OH
1
;
Jin Yeong YONG
;
In Soon WHANG
Author Information
1. Department of Radiation Oncology, National Medical Center, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Malignant Small Cell Tumor of Thoracopulmonary Region;
Radiation
- MeSH:
Cytogenetics;
Diagnosis, Differential*;
Drug Therapy;
Lung;
Lymphoma;
Microscopy;
Neuroblastoma;
Neuroectodermal Tumors, Primitive, Peripheral;
Osteosarcoma;
Pleura;
Rhabdomyosarcoma, Embryonal;
Sarcoma, Ewing;
Thoracic Wall
- From:Journal of the Korean Society for Therapeutic Radiology
1991;9(1):117-122
- CountryRepublic of Korea
- Language:English
-
Abstract:
Malignant small round cell tumor (SRCT) of the thoracopulmonary region appears to originate in the soft tissues of the chest wall or the peripheral lung. A differential diagnosis of poorly differentiated small round cell tumors which include Ewing's sarcoma of bone and soft tissue, embryonal rhabdomyosarcoma, Askin tumor, neuroblastoma, peripheral neuroectodermal tumor, small cell osteogenic sarcoma and lymphoma are after difficult by light microscopy alone. In recent, by the extensive studies electron microscopic examination, histochemical study, immunochemical study, cytogenetics and gene analysis, these tumors may be derived from the primitive and pluripotential cells, differentiating into mesenchymal, epithelial and neural features in variable proportions. Treatment for SRCT of thoracopulmonary regin is not determined because of massive involvement of the lung, pleura or soft tissues of the chest wall resulted in a dismal outcome despite aggressive surgery, irradiation and chemotherapy.
