A Neonatal Case of Symptomatic Congenital Cytomegalovirus Infection with Hearing Defect.
- Author:
Sung Jun JANG
1
;
Yoon Jung CHO
;
Sang Lak LEE
;
Joon Sik KIM
;
Tae Chan KWON
Author Information
1. Department of Pediatrics, School of Medicine, Keimyung University, Taegu, Korea.
- Publication Type:Case Report
- Keywords:
CMV infection;
Hearing loss;
Newborn
- MeSH:
Anemia;
Brain;
Cytomegalovirus Infections*;
Cytomegalovirus*;
Evoked Potentials, Auditory;
Exanthema;
Fetal Growth Retardation;
Follow-Up Studies;
Ganciclovir;
Hearing Loss;
Hearing Loss, Sensorineural;
Hearing*;
Humans;
Incidence;
Infant, Newborn;
Jaundice;
Live Birth;
Male;
Microcephaly;
Outpatients;
Parturition;
Polymerase Chain Reaction;
Purpura;
Thrombocytopenia
- From:Journal of the Korean Pediatric Society
2001;44(2):205-210
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cytomegalovirus(CMV) is one of the leading cause of intrauterine infections of man with an incidence ranging from 0.48% to 2.2% of all live births. Although the majority of CMV-infected newborns are clinically asymptomatic at birth, some will have signs of congenital infection : Intrauterine growth retardation, petechial or purpuric rash, microcephaly, anemia, thrombocytopenia, jaundice, hepatosplenomegaly and intracranial calcification. We experienced a case of symptomatic congenital CMV infection in a 1-day-old male who presented generalized petechiae, hepatosplenomegaly, anemia, thrombocytopenia. Urine PCR and viral culture for CMV were positive, and a brain CT revealed ventriculomegaly and periventricular calcification. And auditory evoked potential revealed left sensorineural hearing loss. He received ganciclovir treatment for 6 weeks, was discharged in good health, and continued conunder follow-up at the outpatient department.
