A Case of Acute Lithium Intoxication Treated with Continuous Venovenous Hemodiafiltration.
- Author:
Soon Young KO
1
;
Tae Ho SEO
;
Seung Min LEE
;
Jung Hwan PARK
;
Young Il JO
;
Seung Ho YOO
;
Jong Ho LEE
Author Information
1. Department of Internal Medicine, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, Korea. nephlee@kuh.ac.kr
- Publication Type:Case Report
- Keywords:
Lithium;
Dialysis;
Hemodiafiltration
- MeSH:
Dialysis;
Hemodiafiltration*;
Lithium*;
Mood Disorders;
Renal Dialysis
- From:Korean Journal of Nephrology
2007;26(3):382-385
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lithium is commonly used for the treatment of bipolar affective disorders. Lithium therapy has a narrow therapeutic window, which can lead to various neurologic, cardiovascular, and renal side effects. Dialysis is recommended for the treatment of severe lithium toxicity, but conventional hemodialysis can cause post-dialysis rebound of serum lithium level. We report a case of lithium intoxication in which continuous venovenous hemodiafiltration (CVVHDF) was successfully used in reducing toxicity. CVVHDF provides excellent lithium clearance, and prevents post-therapy lithium rebound by allowing a progressive removal of intracellular lithium. It could become a modality of choice for lithium intoxication.
