Graves' Disease Associated with Klinefelter's Syndrome.
10.3349/ymj.2004.45.2.341
- Author:
Jong Suk PARK
1
;
Chul Sik KIM
;
Joo Young NAM
;
Dol Mi KIM
;
Soo Jee YOON
;
Chul Woo AHN
;
Bong Soo CHA
;
Sung Kil LIM
;
Kyung Rae KIM
;
Hyun Chul LEE
;
Kap Bum HUH
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. acw@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Klinefelter's syndrome;
Graves' disease;
primary hypogonadism
- MeSH:
Adult;
Graves' Disease/*etiology/radionuclide imaging;
Human;
Hypogonadism/*etiology/genetics/pathology;
Klinefelter Syndrome/*complications/genetics/pathology;
Male
- From:Yonsei Medical Journal
2004;45(2):341-344
- CountryRepublic of Korea
- Language:English
-
Abstract:
Klinefelter's syndrome is one of the most common forms of primary hypogonadism and infertility in males. It is characterized by small and firm testes, gynecomastia, azoospermia, and an elevated gonadotropin level. The frequencies of diabetes mellitus, breast cancer, and germ cell neoplasia increases in Klinefelter's syndrome. We report upon a 35 year-old male patient with Graves' disease in association with Klinefelter's syndrome; as confirmed by chromosome analysis. The patient is being treated with antithyroid medication for Graves' disease and by testosterone replacement for Klinefelter's syndrome.