A Case of Type 1 Renal Tubular Acidosis Accompanying Renal Stone and Nephrocalcinosis Caused by Hypocitraturia.
- Author:
Dong Il SHIN
1
;
Hyun Jung TAE
;
Yong Bum PARK
;
Sun Hee PARK
;
Eun Young CHAE
;
Yoon Sik CHANG
Author Information
1. Department of Internal Medicine, Medical College, The Catholic University of Korea, Seoul, Korea. ysc543@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Renal stone;
Hypocitraturia;
Type 1 RTA
- MeSH:
Acidosis, Renal Tubular*;
Adolescent;
Ammonium Compounds;
Calcium;
Citric Acid;
Humans;
Male;
Nephrocalcinosis*
- From:Korean Journal of Nephrology
2002;21(3):469-474
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Renal stone and nephrocalcinosis are common clinical manifestations of type 1 renal tubular acidosis. In normal state, citrate plays the most critical role in suppressing stone formation as it combines with calcium. In type 1 RTA, increased reabsorption of citrate in proximal tubule results in low citrate excretion, which precipitates renal stone formation. We report a case of type 1 RTA accompanying renal stone and nephrocalcinosis caused by hypocitraturia. A 16-year-old male patient who had renal stone and nephrocalcinosis showed hypocitraturia. Incomplete type 1 RTA was proved as the cause of hypocitraturia by bicarbonate and ammonium loading test in the patient.
