Maxillofacial Enlargement in Secondary Hyperparathyroidism Successfully Treated by Limited Parathyroidectomy and Paricalcitol.
- Author:
Se Won OH
1
;
Young Mo LEE
;
Jeong Yup KIM
;
Joon Kwang WANG
;
Ko Gang JEE
;
Heui Jung PYO
;
Sang Il SUH
;
Seong Eun KIM
;
Jae Bok LEE
;
Ji Eun LEE
;
Seung Won LEE
;
Young Joo KWON
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Korea University Medical Center, Korea. yjkwon@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Renal osteodystrophy;
Hyperparathyroidism;
secondary;
Maxillas
- MeSH:
Adult;
Ergocalciferols;
Hand;
Humans;
Hyperparathyroidism;
Hyperparathyroidism, Secondary;
Korea;
Mandible;
Maxilla;
Neck;
Parathyroid Hormone;
Parathyroidectomy;
Renal Dialysis;
Renal Osteodystrophy
- From:Korean Journal of Nephrology
2011;30(6):671-675
- CountryRepublic of Korea
- Language:English
-
Abstract:
Maxillary enlargement is a rare complication of secondary hyperparathyroidism (SHPT). A 35-year-old Korean man undergoing chronic hemodialysis presented with a painless enlargement involving the maxilla and mandible. Plain radiography and CT scan showed bony expansion at the maxilla and mandible with multiple radiolucency. Serum intact parathyroid hormone (iPTH) was >1,600 pg/mL. Tc-99m sestamibi (MIBI) parathyroid scan and neck sonogram were compatible with SHPT. He underwent limited parathyroidectomy and commenced a course of paricalcitol. Fifteen months after surgery, maxillary enlargement and bony resorptions involving both hands markedly improved. Thirty-six months after the surgery, the serum iPTH level was 109.3 pg/mL. This is the first report in Korea documenting a patient with maxillary enlargement in SHPT who was successfully treated with limited parathyroidectomy and paricalcitol.