Drug-induced Skin Hyperpigmentation after Usual Dosage of Bismuth-Containing Compound Medication in a Kidney Transplant Patient.
- Author:
Woosuk CHOI
1
;
Hanul CHOI
;
Ji Yong JUNG
;
Jae Hyun CHANG
;
Wookyung CHUNG
;
Hyun Hee LEE
Author Information
1. Division of Nephrology, Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science, Korea. lhh90@gilhospital.com
- Publication Type:Case Report
- Keywords:
Bismuth;
Hyperpigmentation;
Kidney transplantation
- MeSH:
Acute Kidney Injury;
Bismuth;
Foot;
Hand;
Humans;
Hyperpigmentation;
Kidney;
Kidney Transplantation;
Liver;
Male;
Middle Aged;
Rejection (Psychology);
Skin;
Transplants
- From:Korean Journal of Nephrology
2011;30(6):682-685
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 59-year-old male presented with multiple hyperpigmented skin with hyperkeratotic scaly patches on hands, feet and face. Bismuth containing compound had been prescribed two months before then due to epigastric pain, an adverse effect of steroid pulse therapy for acute rejection of transplanted kidney. Laboratory findings showed acute kidney injury and elevated liver enzyme. He stopped taking bismuth containing compound and all symptoms were gone after two months. Although there is no report on interaction between bismuth and immunosuppressant, it requires precaution to prescribe bismuth containing compounds in transplanted patients with acute kidney injury.