A Case of Complete Remission of Mucosa-associated Lymphoid Tissue Lymphoma of the Urinary Bladder after Eradication of Helicobacter Pylori.
10.3904/kjm.2014.87.2.229
- Author:
Sunpyo LEE
1
;
Myung Soo CHOO
;
Min Hee RYU
;
Minjeong SONG
;
Seyoung SEO
;
Yumun JEONG
;
Myeongsook SEO
;
Jooryung HUH
Author Information
1. Department of Internal Medicine, Asan medical Center, University of Ulsan College of Medicine, Seoul, Korea. miniryu@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Urinary Bladder;
Lymphoma;
Mucosa-associated Lymphoid Tissue;
Helicobacter pylori;
Antibiotics
- MeSH:
Anti-Bacterial Agents;
Biopsy;
Cystoscopy;
Female;
Helicobacter pylori*;
Hematuria;
Humans;
Lymphoid Tissue;
Lymphoma;
Lymphoma, B-Cell, Marginal Zone*;
Middle Aged;
Neoplasm Metastasis;
Urease;
Urinary Bladder*
- From:Korean Journal of Medicine
2014;87(2):229-233
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary lymphoma of the urinary bladder is rare, comprising 0.2% of extranodal lymphomas. The predominant subtype of mucosa-associated lymphoid tissue (MALT) is extranodal marginal zone lymphoma. We report a case of MALT lymphoma of the urinary bladder in a 53-year-old female patient presenting with a five-year history of persistent hematuria and urinary frequency. A cystoscopy revealed multiple nodular lesions at the posterior wall and trigone of the bladder. The tissue obtained by cold-cup biopsy revealed lymphoid infiltration consistent with low-grade MALT lymphoma. Image studies revealed that the tumor originated from the urinary bladder and there was no evidence of metastases. The patient was positive for a rapid urease test. Because of the relationship between gastric MALT lymphoma and Helicobacter pylori, the patient was treated with antibiotics to eradicate Helicobacter pylori. The lymphoma subsequently disappeared and the patient has remained in persistent complete remission for eight years.
