Multidrug-Resistant Gram-Positive Bacterial Infections.
10.3904/kjm.2015.88.5.487
- Author:
Younghee JUNG
1
;
Hong Bin KIM
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. hbkimmd@snu.ac.kr
- Publication Type:Review
- Keywords:
Methicillin-resistant Staphylococcus aureus;
Vancomycin-resistant enterococcus;
Penicillin-resistant Streptococcus pneumoniae
- MeSH:
Anti-Bacterial Agents;
Bacteria;
Bacterial Infections;
Drug Resistance, Microbial;
Enterococcus;
Epidemiology;
Gram-Positive Bacteria;
Gram-Positive Bacterial Infections*;
Korea;
Methicillin-Resistant Staphylococcus aureus;
Risk Factors;
Streptococcus pneumoniae;
Treatment Outcome
- From:Korean Journal of Medicine
2015;88(5):487-501
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Antimicrobial resistance threatens the effective treatment of bacterial infections and is a serious problem worldwide. Multidrug-resistant bacteria are difficult to treat and the treatment outcome is worse than with susceptible bacteria. In Korea, the antibiotic resistance rates of the major Gram-positive bacteria methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococcus (VRE), and penicillin-resistant Streptococcus pneumoniae (PRSP) are very high. Clinicians should know the risk factors for developing multidrug-resistant bacterial infection, update the changing local epidemiology of resistant bacteria, and choose appropriate antibiotics in clinical practice. The overuse and misuse of broad spectrum antibiotics should be avoided. This review focuses on the epidemiology and risk factors of MRSA, VRE, and PRSP, the major multidrug-resistant Gram-positive bacteria.
