Clinical Efficacy of Body Mass Index as Predictor of In Vitro Fertilization and Embryo Transfer Outcomes.
10.3346/jkms.2006.21.2.300
- Author:
Seung Yup KU
1
;
Sang Don KIM
;
Byung Chul JEE
;
Chang Suk SUH
;
Young Min CHOI
;
Jung Gu KIM
;
Shin Yong MOON
;
Seok Hyun KIM
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Seoul, Korea. seokhyun@plaza.snu.ac.kr
- Publication Type:Original Article
- Keywords:
Body Mass Index;
Fertilization;
In Vitro;
Embryo Transfer;
Reproductive Techniques;
Assited
- MeSH:
Treatment Outcome;
Prognosis;
Pregnancy;
Obesity/complications/pathology;
Infertility, Female/complications/pathology/therapy;
Humans;
*Fertilization in Vitro;
Female;
*Embryo Transfer;
Embryo Implantation;
*Body Mass Index;
Adult
- From:Journal of Korean Medical Science
2006;21(2):300-303
- CountryRepublic of Korea
- Language:English
-
Abstract:
The aim of this study was to evaluate the clinical efficacy of body mass index (BMI) as a predictor of in vitro fertilization and embryo transfer (IVF-ET) outcomes. Two hundred twenty-three IVF-ET cycles in 164 patients under 37 yr using GnRH agonist long protocols were included in this retrospective study. All of the selected cases were divided into two groups by a cutoff of 24 kg/m2 and these two groups were compared in regard to the outcomes of IVF-ET. There were no significant differences between group 1 (BMI <24 kg/m2) and group 2 (BMI > or = 24 kg/m2) in age, basal serum FSH level, estradiol (E2) level and endometrial thickness on hCG day, number of retrieved oocytes and transferred embryos. However, higher doses of gonadotropins were used in group 2 (30.8+/-12.7 ampoules vs. 35.4+/-15.3 ampoules, p=0.051). The clinical pregnancy rate was significantly lower in group 2 (25.9% vs. 10.5%, p=0.041) and implantation rate tended to be lower in group 2 (12.7% vs. 6.8%, p=0.085). BMI > or = 24 kg/m2 can be a candidate prognosticator of IVF-ET outcomes.
