Colonic Langerhans Cell Histiocytosis Presenting as an Isolated Polyp.
- Author:
Hyun Woong SEO
1
;
Koon Hee HAN
;
Sunghun KIM
;
Man Yong HONG
;
Jung Ho YUN
;
Dae Woon EOM
;
Gab Jin CHEON
Author Information
1. Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea. gi@gnah.co.kr
- Publication Type:Case Report
- Keywords:
Langerhans-cell histiocytosis;
Colon;
Polyps;
S-100 protein;
CD1a antigen
- MeSH:
Antigens, CD1;
Colon;
Colon, Descending;
Colonoscopy;
Eosinophils;
Histiocytosis, Langerhans-Cell;
Humans;
Langerhans Cells;
Male;
Mass Screening;
Polyps;
S100 Proteins;
SNARE Proteins
- From:Korean Journal of Medicine
2013;84(5):704-707
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 56-year-old male underwent a screening colonoscopy. An 8-mm sessile polyp was removed from the descending colon using snare polypectomy. Histology showed Langerhans cells and eosinophil infiltration of the submucosa. Immunohistochemical staining was positive for S-100 protein and CD1a antigen, which confirmed the diagnosis of Langerhans-cell histiocytosis. On further workup, there was no evidence of involvement of any other organs. Here, we report a very rare case of colonic Langerhans-cell histiocytosis presenting as an isolated polyp.
