Unusual Complication of Crohn's Disease: Portal Hypertension Related with Rapid Progression of Portal Vein and Superior Mesenteric Vein Thrombosis.
- Author:
Da Yeon OH
1
;
Hye Kyung JUNG
;
Kyoung Joo KWON
;
Jae In RYU
;
Myung Eun SONG
;
Kwon YOO
;
Il Hwan MOON
Author Information
1. Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea. junghk@ewha.ac.kr
- Publication Type:Case Report
- Keywords:
Crohn's disease;
Venous thromboembolism;
Portal hypertension
- MeSH:
Colitis, Ulcerative;
Crohn Disease;
Humans;
Hypertension, Portal;
Intracranial Thrombosis;
Mesenteric Veins;
Portal Vein;
Protein C;
Protein S;
Pulmonary Embolism;
Siblings;
Thromboembolism;
Thrombosis;
Twins, Monozygotic;
Venous Thromboembolism;
Venous Thrombosis
- From:Korean Journal of Medicine
2013;84(5):713-717
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Thromboembolic events are rare among systemic complications of inflammatory bowel disease; however, they are a significant cause of mortality when they occur. Several reports have considered thromboembolic events in patients with ulcerative colitis presenting with venous or arterial thromboembolism, such as cerebral thrombosis, deep vein thrombosis, pulmonary thromboembolism, portal vein thrombosis, or mesenteric vein thrombosis. However, increased coagulability related to Crohn's disease is extremely rare compared with that of ulcerative colitis. We report a case of a 42-year-old man with complicated portal hypertension that occurred due to extensive portal vein and mesenteric vein thrombosis. He had a monozygotic twin brother who was also in remission with Crohn's disease. The patient showed protein C and protein S deficiencies; however, he recovered with early anticoagulation therapy.
