Quantitative Analysis of p53 Expression in Carcinoma of the Uterine Cervix.
- Author:
Chi Seok AHN
;
Eun Hwan JEONG
;
Tae Soo LEE
;
Rho Hyun SEONG
- Publication Type:Original Article
- MeSH:
Cervix Uteri*;
Female;
Immunohistochemistry
- From:Korean Journal of Gynecologic Oncology and Colposcopy
1994;5(3):11-18
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This studly was perormed 10 define the role of compulerized quantitative analysis in ewalualion for overexpression of p53 by immunohistochemistry. Total and ladeled cells wers counted automatically using commercially available software for color-image analysis. In 16 uterine cerwical carcinomas, the p53 ladeling index calculted bycomputerized5quantitatiwe analysis was 9.22%+/-8.70% and by visual analysis 5.90+/-6.51%. The present results suggest that the computerized quantitative analysis may be valuadle in objective interetation of immunohistochemical expression of p53 and reliable than conventional ways of visual analysis.
