The Effect of Ginkgo Biloba to Retinal Microcirculation.
- Author:
Dong Joon LEE
1
;
Hee Bae AHN
;
Sae Heun RHO
Author Information
1. Department of Ophthalmology, College of Medicine, Dong-A University, Pusan, Korea. shrho@donga.ac.kr
- Publication Type:Original Article
- Keywords:
Ginkgo biloba;
Blood flow;
Blood volume;
Blood velocity
- MeSH:
Blood Flow Velocity;
Blood Volume;
Ginkgo biloba*;
Microcirculation*;
Retina;
Retinaldehyde*;
Rheology
- From:Journal of the Korean Ophthalmological Society
2002;43(8):1522-1527
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We evaluated the microcircular changes of optic disc, peripapillary and macular area in healthysubjects who had taken Gingko biloba extract. METHODS: 10 healthy subjects (20 eyes) took Gingko biloba extract 40mg three times daily. Confocal scanning laser flowmetry (Heidelberg Retina Flowmetry, Heidelberg Engineering, Heidelberg, Germany) was used to measure the changes of microcirculation at before and after 2, 4 hours, 1 day, 1, 2, 3, 4 weeks. RESULTS: After administration of Gingko biloba extract, blood velocity, blood flow and blood volume in optic disc, peripapillary and macular area increased in all periods but statistically significant in 1 day, 1, 2, 3, 4 weeks except blood volume of macular area in 1 day. No side effects related to Gingko biloba extract were found. CONCLUSIONS: Gingko biloba extract increased microcircular blood velocity, flow, and volume in healthysubjects.
