A Case of Intracerebral Aspergillus Abscess Presenting as Cerebral Infarction.
- Author:
Sang Su KIM
1
;
Jae Ik JEONG
;
Jae Kwan CHA
;
Sang Ho KIM
;
Jae Woo KIM
;
Hyung Dong KIM
Author Information
1. Department of Neurology, DongA University College of Medicine.
- Publication Type:Case Report
- MeSH:
Abscess*;
Amphotericin B;
Aspergillosis;
Aspergillus fumigatus;
Aspergillus*;
Brain;
Brain Abscess;
Candida;
Central Nervous System;
Cerebral Infarction*;
Cryptococcus;
Diabetes Mellitus;
Facial Paralysis;
Fungi;
Granuloma;
Headache;
Humans;
Infarction, Middle Cerebral Artery;
Magnetic Resonance Imaging;
Male;
Meningitis;
Meningoencephalitis;
Middle Aged;
Mucor;
Nervous System;
Nocardia;
Paresis;
Rare Diseases;
Sleep Stages
- From:Journal of the Korean Neurological Association
1998;16(1):87-90
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND SIGNIFICANCE: Fungal infection of the central nervous system can be attributable to Cryptococcus, Nocardia, Mucor, Candida, and rarely Aspergillus. The types of nervous system involvement by Aspergillus can be divided into 4 groups : meningitis, meningoencephalitis, brain abscess, and single solid granuloma. Aspergillosis involving the central nervous system is a rare disease. Aspergillosis presenting as cerebral infarction has been rarely reported. We experienced one case of intracerebral abscess caused by Aspergillus, presenting as cerebral infarction. CASE: A 54-year-old male, with a history of diabetes mellitus for 7 years, was admitted with headache for 1 month. Initial CSF findings showed pleocytosis(180/ul), and increased protein(79mg/dl). On the 2nd admission day, the patient showed left hemiparesis, left facial palsy of central type and drowsiness. Brain MRI revealed right MCA infarction. Neurologic status was stationary for almost 2wks. The WBC count of CSF was increased to 1150/ul on the 14th admission day, and antituberculous medication was started. On the 27th admission day, deep drowsy mentality was noted. Treatment with steroid was done and then mentality was improved to drowsiness. Brain abscess was found in right frontotemporal area and there were herniation signs on the 29th admssion day. Aspiration was done. Aspergillus fumigatus was grown on fungus culture of CSF and amphotericin B was started. CONCLUSION: We report a rare case of intracerebral Aspergillosis, manifested by right MCA infarction and brain abscess.
