In vivo H MR spectroscopy of human brain in six normal volunteers.
10.3348/jkrs.1993.29.5.853
- Author:
Bo Young CHOE
;
Tae Suk SUH
;
Yong Whee BAHK
;
Kyung Sub SHINN
- Publication Type:Original Article
- MeSH:
Biochemistry;
Brain*;
Diagnosis;
Healthy Volunteers*;
Humans*;
Magnetic Resonance Spectroscopy*;
Protons
- From:Journal of the Korean Radiological Society
1993;29(5):853-860
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In vivo 1H MR spectroscopic studies were performed on the human brain in six normal volunteers. Some distinct proton metabolites, such as N-acetylaspartate (NAA), creatine/phosphoccreatine (Cr), choline/phosphocholine (Cho), myo-inostitol (Ins) and lipid (fat) were clearly identified in normal brain tissues. The signal intensity of NAA resonance is strongest. The standard ratios of metabolites from the normal brain tissues in specific regions were obtained for the references of further in vivo 1H MR spectroscopic studies. Our initial results suggest the in vivo 1H MR spectroscopy may provide more precise diagnosis on the basis of the metabolic informations on brain tissues. The unique ability of in vivo 1H MR spectroscopy to offer noninvasive information about tissue biochemistry in patients will stimulate its impact on clinical research and disease diagnosis.
