Thrombolysoangioplasty in chronic, long segmental occlusive arterial disease.
10.3348/jkrs.1993.29.5.954
- Author:
Tae Woong CHUNG
;
Jae Kyu KIM
;
Byung Kwan KOH
;
Jin Yup KIM
;
Jeoung Jin SEO
;
Hyeoung Keun KANG
- Publication Type:Original Article
- MeSH:
Angiography;
Arteries;
Follow-Up Studies;
Hemorrhage;
Humans;
Jeollanam-do;
Lower Extremity;
Recurrence;
Urokinase-Type Plasminogen Activator
- From:Journal of the Korean Radiological Society
1993;29(5):954-960
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
From July 1988 to September 1992, we experienced 15 cases of thrombolysoangioplasty (TLA) at Chonnam University Hospital. Among 15 cases, 5 had claudication (Clinical stage II according to Modified Fontaine Classification), pain at rest (III), and gangrene(IV). Duration of symptoms was 1-7 months except patients of clinical stage IV unable to guess occlusion age. The occlusion length was 5-10cm in 8 cases, 10-20cm in 4 cases, and above 30cm in 2 cases. In all cases, thromolytic therapy was performed with intraarterial urokinase infusion. The total amount of urokinase ranged from 300,000 IU to 2,000,000 IU and infusion time ranged from 2 to 50 hours except three cases infused bolus dose only. Complete successful TLA was defined as technical (less than 50% of residual stenosis) and clinical success. Partial success was defined as technical success but clinical failure. Follow-up angiography could be performed in 8 cases. Overall initial success rate was 86.6% (13/15). Among them. Complete success was in 11 cases and partial success was in 2 cases. Recurrence of disease was not noted on all cases(n=8). Severe complications, such as hemorrhage, did not occurred. TLA was considered to be effective and safe way to recanalized chronic long artery occlusion in lower extremity.
