Posterior Leukoencephalopathy Syndrome Following Intravenous Chemotherapy for Medulloblastoma in a Child.
- Author:
Sung Bum AHN
1
;
Shin Hyuk KANG
;
Yong Gu CHUNG
;
Hoon Kap LEE
Author Information
1. Department of Neurosurgery, College of Medicine, Korea University, Seoul, Korea. hermes23@medimail.co.kr
- Publication Type:Case Report
- Keywords:
Posterior leukoencephalopathy;
Chemotherapy;
Medulloblastoma
- MeSH:
Child*;
Drug Therapy*;
Humans;
Hypertension, Malignant;
Immunosuppressive Agents;
Leukoencephalopathies;
Male;
Medulloblastoma*;
Nimustine;
Posterior Leukoencephalopathy Syndrome*;
Pre-Eclampsia;
Seizures;
Vincristine
- From:Journal of Korean Neurosurgical Society
2004;36(6):493-495
- CountryRepublic of Korea
- Language:English
-
Abstract:
Posterior leukoencephalopathy syndrome(PLES) is a rare neurological complication which is associated with malignant hypertension, pre-eclampsia, and some drugs including immunosuppressive agents. A 9-year-old boy who had cerebellar medulloblastoma showed seizure on the seventeenth day after intravenous chemotherapy including ACNU and vincristine. Radiologic findings were consistent with those of PLES due to vasospasm. After hypertensive therapy, the symptoms were improved. We present a case of PLES with medulloblastoma which developed following chemotherapy with the regimen of medulloblastoma in a child.
