Intravenous Vitamin K-induced Cardiovascular Collapse : A case report.
10.4097/kjae.2007.52.4.461
- Author:
Sang Jin PARK
1
;
Chae Rim SEONG
;
Dae Lim JEE
Author Information
1. Dalseong-gun Public Health Center, Korea.
- Publication Type:Case Report
- Keywords:
anaphylaxis;
cardiovascular collapse;
vitamin K.
- MeSH:
Administration, Intravenous;
Anaphylaxis;
Blood Pressure;
Dyspnea;
Ephedrine;
Exanthema;
Female;
Flushing;
Humans;
Hypotension;
Lung;
Middle Aged;
Torso;
Vitamin K;
Vitamins*
- From:Korean Journal of Anesthesiology
2007;52(4):461-464
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A cardiovascular collapse, due to preoperatively administered intravenous vitamin K (phytonadione), was experienced in a 59-year-old woman who was scheduled to undergo a left upper lung lobectomy. The patient developed sudden facial flushing, an upper torso rash, dyspnea, palpitation, and severe hypotension about 2 min after the intravenous administration of approximately 2 mg of vitamin K. Immediate hydration and an injection of 20 mg ephedrine restored her blood pressure to the preoperative level within 5 min. The patient recovered without any sequelae, but the operation was postponed. The patient's symptoms seemed to be due to an anaphylactoid reaction or anaphylaxis following the intravenous administration of vitamin K. This case report suggests that physicians should carefully review the indications of vitamin K prior to administration, even at low doses.
