Concurrent IgA Nephropathy and Minimal Change Disease in a Patient with Polycythemia Vera: A Case Report.
- Author:
Young Jong JUNG
1
;
Beom KIM
;
Kyoung Hyoub MOON
;
Hee Sup KIM
;
Ji Ho KIM
;
Soo Yeun KIM
;
Bong Seog KIM
;
Youn Mi CHOI
;
Yong Mee CHO
Author Information
1. Department of Internal Medicine, Seoul Veterans Hospital, Seoul, Korea. glom@hanafos.com
- Publication Type:Case Report
- Keywords:
Polycythemia vera;
IgA nephropathy;
Minimal change glomerulopathy
- MeSH:
Bone Marrow;
Glomerulonephritis;
Glomerulonephritis, IGA;
Hematopoietic Stem Cells;
Hemoglobins;
Humans;
Hydroxyurea;
Immunoglobulin A;
Nephrosis, Lipoid;
Phlebotomy;
Polycythemia;
Polycythemia Vera;
Proteinuria;
World Health Organization
- From:Korean Journal of Nephrology
2008;27(6):733-737
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Polycythemia vera is a hematopoietic stem cell disease, characterized by sustained and excessive proliferation of erythrocytic, granurocytic and megakaryocytic cells in the bone marrow resulting in pancytosis in peripheral blood. There have been a few reports of glomerulonephritis with polycythemia vera, most of which were IgA nephropathy. We report a case of a polycythemia vera associated with proteinuria. We confirmed the polycythemia vera according to World Health Organization criteria. Renal pathology showed IgA nephropathy and minimal change disease. Periodic phlebotomy was done and hydroxyurea was administered without specific managements for renal disease. After 3-month treatment, hemoglobin level decreased and proteinurea disappeared.
