Synthesis and bioactivities of some cis-diamin complex of piperidine or morpholine and other amin containing platin (II)
- Author:
Da Thi Tran
- Publication Type:Journal Article
- Keywords:
piperidine
- MeSH:
Piperidine;
Morpholine;
Pharmaceutical Preparations
- From:Pharmaceutical Journal
2002;318(10):6-8
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Three complexes of cis-dichloro (piperdine) (amine) platinum (II) and there complexes of cis-dichloro (morpholine) (amine) platinum(II) including [Pt(Pip)(Pyridine)Cl2], {Pt(Pip)(o -{Pt(Pip)(o-Toluidine)Cl2] have been synthesized and characterized by elemental analysis< molar conductivity, IR and Raman spectral studies. The complexes were tested for biological activities and found to be capable of inhibiting the growth of some human cancer cells. This result showed that the presence of piperidine in prepared complexes influenced on their biological activities clearer than as compared to the complexes containing morpholine.
