Successful desensitization of a patient with albumin hypersensitivity.
10.4168/aard.2017.5.2.117
- Author:
So Yoon JUNG
1
;
Yun Jung CHOI
;
Seung Hyun LEE
;
Hye Ryun KANG
;
Dong In SUH
Author Information
1. Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. dongins0@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Drug hypersensitivity syndrome;
Anaphylaxis;
Immunologic desensitization
- MeSH:
Adolescent;
Anaphylaxis;
Desensitization, Immunologic;
Drug Hypersensitivity Syndrome;
Humans;
Hypersensitivity*;
Hypersensitivity, Immediate;
Male;
Premedication;
Receptors, Leukotriene
- From:Allergy, Asthma & Respiratory Disease
2017;5(2):117-120
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
There have been few cases of albumin hypersensitivity reported, and there is limited information on this condition. When a patient is anaphylactic to a certain drug and no alternative drug is available to treat the underlying condition, desensitization is a reasonable option and can be performed successfully to treat the patient. A standard 12-step, 3-solution rapid desensitization protocol allows the safe readministration of a medication after certain types of immediate hypersensitivity. However, we demonstrated that a new 10-step, 1-solution desensitization protocol using antihistamine and leukotriene receptor antagonist as premedications, which was effective and safe in a patient with hypersensitivity. We report a 13-year-old boy with Gorham-stout syndrome who was presented with newly acquired albumin anaphylaxis and successfully treated with the 10-step rapid drug desensitization protocol.
