Use of the n-butyl cyanoacrylate adhesive and the polyglactine thread suture for corneal rhaphy in rabbit (Oryctolagus cunicullus).
- Author:
Francisco Claudio Dantas MOTA
1
;
Duvaldo EURIDES
;
Patricia Maria Coletto FREITAS
;
Marcelo Emilio BELETTI
;
Michelle Rodriques GOULART
;
Livia Maria Ferreira CUNHA
;
Luiz Antonio Franco DA SILVA
;
Maria Clorinda Soares FIORAVANTI
Author Information
1. College of Veterinary Medicine, Federal University of Uberlandia, Minas Gerais, Brasil. dantasmota@yahoo.com.br
- Publication Type:Original Article ; Comparative Study ; Evaluation Studies
- Keywords:
rabbit;
cornea;
surgery;
suture;
synthetic adhesive
- MeSH:
Animals;
Cornea/*injuries/*surgery;
Enbucrilate/*therapeutic use;
Female;
Male;
Polyglactin 910/therapeutic use;
Rabbits/*surgery;
*Sutures;
Tissue Adhesives/*therapeutic use;
*Wound Healing
- From:Journal of Veterinary Science
2004;5(3):267-270
- CountryRepublic of Korea
- Language:English
-
Abstract:
The aim of this study was to evaluate the cicatricial repair of perforating cornea in rabbits, by using the Nbutyl cyanoacrylate adhesive compared to the 910-polyglactine thread suture through macroscopic and histological assays. Corneas from 18 adult rabbits were perforated and subsequently occluded with N-butyl cyanoacrylate synthetic adhesive (right cornea) or by separated single points using the 910-polyglactine thread (left cornea). The rabbits were divided into groups containing three animals per group. Examination after 7, 15, and 30 days post-operative showed that both the synthetic adhesive and the suture were efficient in the occlusion of the surgical wounds, thus stabilizing the intra-ocular content. The N-butyl cyanoacrylate adhesive was shown to be superior to the 910-polyglactine suture thread with regards to the evolution and the organization of the healing process.