BK virus-associated hemorrhagic cystitis after pediatric stem cell transplantation.
10.3345/kjp.2014.57.12.514
- Author:
Seung Beom HAN
1
;
Bin CHO
;
Jin Han KANG
Author Information
1. Department of Pediatrics, The Catholic University of Korea College of Medicine, Seoul, Korea. chobinkr@catholic.ac.kr
- Publication Type:Review
- Keywords:
Cystitis;
Stem cell transplantation;
BK virus;
Child
- MeSH:
BK Virus;
Cell Transplantation;
Child;
Cystitis*;
Early Diagnosis;
Humans;
Incidence;
Mesna;
Nephrology;
Stem Cell Transplantation*;
Stem Cells;
Transplants
- From:Korean Journal of Pediatrics
2014;57(12):514-519
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hemorrhagic cystitis is a common stem cell transplantation-related complication. The incidence of early-onset hemorrhagic cystitis, which is related to the pretransplant conditioning regimen, has decreased with the concomitant use of mesna and hyperhydration. However, late-onset hemorrhagic cystitis, which is usually caused by the BK virus, continues to develop. Although the BK virus is the most common pathogenic microorganism of poststem cell transplantation late-onset hemorrhagic cystitis, pediatricians outside the hemato-oncology and nephrology specialties tend to be unfamiliar with hemorrhagic cystitis and the BK virus. Moreover, no standard guidelines for the early diagnosis and treatment of BK virus-associated hemorrhagic cystitis after stem cell transplantation have been established. Here, we briefly introduce poststem cell transplantation BK virus-associated hemorrhagic cystitis.
