Clinical Utility and Accuracy of Coaguchek(R) XS, a Reliable Alternative to Laboratory International Normalized Ratio Monitoring in Korean Patients With Atrial Fibrillation.
- Author:
Sung Hea KIM
1
;
Soon Yong SUH
;
Hyun Joong KIM
;
Seong Woo HAN
;
Sang Man JUNG
;
Kyu Hyung RYU
Author Information
- Publication Type:Original Article
- Keywords: Atrial fibrillation; Prothrombin time
- MeSH: Atrial Fibrillation; Humans; International Normalized Ratio; Prothrombin Time; Warfarin
- From:Korean Circulation Journal 2009;39(2):71-74
- CountryRepublic of Korea
- Language:Korean
- Abstract: BACKGROUND AND OBJECTIVES: To evaluate the accuracy and the clinical utility of the Coaguchek(R) XS, a portable point-of-care coagulometer, compared to standard laboratory methods in Korean patients. SUBJECTS AND METHODS: We included 107 patients with atrial fibrillation on long-term oral warfarin therapy. The prothrombin time as expressed by the international normalized ratio (INR) was measured by the portable Coaguchek(R) XS system as well as standard laboratory methods. Agreement between the two methods was defined as a difference of less than 0.3 between the INR values. RESULTS: The INR determined by the portable Coaguchek(R) XS had excellent correlation with the values obtained by standard methods (r=0.984, p<0.01). The INR determined by the portable Coaguchek(R) XS tended to be high among the high INR group values (standard INR>3.0). There was a 91.6% agreement between the two methods. Only nine cases (8.4%) had a difference of more than 0.3; this was mainly noted in the high INR group. CONCLUSION: The portable self-testing of the INR by the Coaguchek(R) XS might be a reliable alternative to hospital based laboratory testing in Korean patients.
