Two Cases of Tuberous Sclerosis Associated with Subependymal Giant Cell Astrocytoma.
- Author:
Yong KO
1
;
Kwang Myung KIM
;
Hwan Yung CHUNG
;
Nam Kyu KIM
;
Suk Jun OH
;
Chan Geum PARK
;
Jung Dal LEE
;
Seung Ro LEE
;
Chang Gok HAHM
Author Information
1. Department of Neurosurgery, School of Medicine Hanyang University, Korea.
- Publication Type:Original Article
- Keywords:
Adenoma sebaceum;
Mental retardation;
Epilepsy;
Phakoma;
Subependymal giant cell astrocytoma
- MeSH:
Astrocytoma*;
Epilepsy;
Humans;
Hydrocephalus;
Intellectual Disability;
Penetrance;
Tuberous Sclerosis*
- From:Journal of Korean Neurosurgical Society
1988;17(3):535-544
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neurosurgical intervention in the syndrome is discussed in the light of two recently treated cases, one of which was admitted due to acute hydrocephalic attack, the other was confirmed by the typical computed tomographic findings as well as the classic triad of adenoma sebaceum, mental retardation and epilepsy. There cases had no family historty and were probably the result of new mutations and variable penetrance. Transcallosal microsurgical excision of tumor was accomplished in both cases and subependymal giant cell astrocytoma was confirmed. The hydrocephalus resolved but subduroperitoneal shunt was required in one case.
