Study for the Lack of Mental Changes to Severe Hyperglycemia in Diabetic Patients with Renal Failure.
- Author:
Hyung Jung WI
1
;
Chang Bum LEE
;
Sung Kwang PARK
;
Sung Kyew KANG
;
Chun Gyu LIM
;
Kyung Taek YUN
;
Eun Joo PARK
;
Sang Woong HAN
;
You Hern AHN
;
Ho Jung KIM
Author Information
1. Department of Internal Medicine, Hanyang University Kuri Hospital, Korea.
- Publication Type:Original Article
- Keywords:
Hyperglycemia;
Mental changes;
Renal failure;
Osmotic diuresis
- MeSH:
Blood Glucose;
Coma;
Diuresis;
Humans;
Hyperglycemia*;
Osmolar Concentration;
Renal Dialysis;
Renal Insufficiency*;
Sodium
- From:Korean Journal of Nephrology
2000;19(6):1086-1090
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In diabetic patients who were being treated with hemodialysis, coma and other neurological deficits did not occur in spite of extremely elevated serum glucose levels. In this report, we compared diabetic patients with renal failure in severe hyperglycemia with nonketotic hyperosmolar coma patients with normal renal function to know what affect mental changes. Mental changes were not present in diabetic patients with renal failure. These patients with renal failure showed more severe hyperglycemia, but corrected serum sodium concentration and calculated effective serum osmolality were low. So it is suggested that corrected serum sodium concentration and effective serum osmolality are more important factor affecting mental changes than high blood glucose levels in diabetic patients with renal failure, due to absence of osmotic diuresis.