Prevention of Venous Thromboembolism in Medical Intensive Care Unit: A Multicenter Observational Study in Korea.
10.3346/jkms.2014.29.11.1572
- Author:
Jinwoo LEE
1
;
Seok Chan KIM
;
Sun Jong KIM
;
Jin Young OH
;
Hyun Kyung LEE
;
Ho Kee YUM
;
Yang Ki KIM
;
Sang Bum HONG
;
Moo Suk PARK
;
Sung Chul HWANG
;
Hyoung Kyu YOON
;
Hak Ryul KIM
;
Jae Hwa CHO
;
Sunghoon PARK
;
Chul Gyu YOO
Author Information
1. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. cgyoo@snu.ac.kr
- Publication Type:Original Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
- Keywords:
Medical Patients;
Intensive Care Units;
Thromboprophylaxis;
Venous Thromboembolism
- MeSH:
Adult;
Age Factors;
Aged;
Cohort Studies;
Female;
Heart Failure/complications;
Heparin, Low-Molecular-Weight/therapeutic use;
Humans;
*Intensive Care Units;
Length of Stay;
Male;
Mechanical Thrombolysis;
Middle Aged;
Republic of Korea;
Respiratory Insufficiency/complications;
Retrospective Studies;
Risk Factors;
Tomography, X-Ray Computed;
Venous Thromboembolism/complications/*prevention & control/therapy
- From:Journal of Korean Medical Science
2014;29(11):1572-1576
- CountryRepublic of Korea
- Language:English
-
Abstract:
Patients admitted to medical intensive care unit (MICU) are at increased risk for venous thromboembolism (VTE); and prophylaxis is recommended. However, the actual range and frequency of VTE prophylaxis administered to MICU patients are not well defined. Patients over 40 yr of age and expected MICU stay of more than 48 hr were eligible for this observational cohort study of 23 MICUs in Korea. Patients already on anticoagulation therapy or those requiring anticoagulation for reasons other than VTE were excluded. Among 830 patients, VTE prophylaxis was given to 560 (67.5%) patients. Among 560 patients, 323 (38.9%) received pharmacoprophylaxis, 318 (38.4%) received mechanical prophylaxis and 81 (9.8%) received both forms of prophylaxis. About 74% of patients in the pharmacoprophylaxis group received low molecular weight heparin and 53% of the patients in the mechanical prophylaxis group used intermittent pneumatic compression. Most of the patients (90%) had more than one risk factor for VTE and the most common risk factor was old age, followed by heart and respiratory failure. In this observational cohort study of 23 MICUs in Korea, 67.5% of patients received thromboprophylaxis. Further studies are needed to clarify the role and efficacy of VTE prophylaxis in Korean critically ill patients.
