Injectable Tissue-Engineered Soft Tissue for Tissue Augmentation.
10.3346/jkms.2014.29.S3.S170
- Author:
Sung Mi RHEE
1
;
Hi Jin YOU
;
Seung Kyu HAN
Author Information
1. Department of Plastic Surgery, Korea University College of Medicine, Seoul, Korea. pshan@kumc.or.kr
- Publication Type:Review
- Keywords:
Cell Therapy;
Soft Tissue;
Tissue Engineering
- MeSH:
Adipocytes/transplantation;
Adipose Tissue/cytology;
Biocompatible Materials;
Connective Tissue/*surgery;
Dermatologic Surgical Procedures/*methods;
Face;
Fibroblasts/transplantation;
Humans;
Hyaluronic Acid/therapeutic use;
Injections, Intradermal;
Mesenchymal Stem Cell Transplantation/*methods;
Mesenchymal Stromal Cells;
Skin;
Skin Aging;
Tissue Engineering/*methods
- From:Journal of Korean Medical Science
2014;29(Suppl 3):S170-S175
- CountryRepublic of Korea
- Language:English
-
Abstract:
Soft tissue augmentation is a process of implanting tissues or materials to treat wrinkles or soft tissue defects in the body. Over the years, various materials have evolved to correct soft tissue defects, including a number of tissues and polymers. Autogenous dermis, autogenous fat, autogenous dermis-fat, allogenic dermis, synthetic implants, and fillers have been widely accepted for soft tissue augmentations. Tissue engineering technology has also been introduced and opened a new venue of opportunities in this field. In particular, a long-lasting filler consisting of hyaluronic acid filler and living human mesenchymal cells called "injectable tissue-engineered soft tissue" has been created and applied clinically, as this strategy has many advantages over conventional methods. Fibroblasts and adipose-derived stromal vascular fraction cells can be clinically used as injectable tissue-engineered soft tissue at present. In this review, information on the soft tissue augmentation method using the injectable tissue-engineered soft tissue is provided.
