Entropy Responses to Endotracheal Intubation during Anesthetic Induction Using Thiopental or Propofol and Succinylcholine.
10.4097/kjae.2006.50.3.272
- Author:
Chong Wha BAEK
1
;
Na Young KO
;
Mi Jeung GWAK
;
Jung Won PARK
;
Yong Hun JUNG
;
Young Cheol WOO
;
Jin Yun KIM
;
Gill Hoi KOO
;
Sun Gyoo PARK
Author Information
1. Department of Anesthesiology and Pain Medicine, College of Medicine, Chung-Ang University, Korea. bjhwa@hanmail.net
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
entropy;
intubaion;
propofol;
thiopental
- MeSH:
Adult;
Anesthesia;
Arousal;
Choline;
Entropy*;
Female;
Fentanyl;
Hemodynamics;
Humans;
Intubation;
Intubation, Intratracheal*;
Propofol*;
Prospective Studies;
Succinylcholine*;
Thiopental*
- From:Korean Journal of Anesthesiology
2006;50(3):272-277
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Thiopental and propofol are commonly used intravenous induction agents and entropy is a new method of assessing depth of anesthesia. In this study we evaluated the entropy responses to endotracheal intubation during anesthetic induction with thiopental or propofol. METHODS: Forty ASA class I and II adult female patients undergoing elective surgeries were enrolled into this randomized, prospective study. At 1 minute after fentanyl 2 microgram/kg, thiopental 5 mg/kg (group T) or propofol 2 mg/kg (group P) was administered for induction. And endotracheal intubation was performed following succiny choline 1 mg/kg. From pre-induction till post-intubation 10 minutes, the entropy and hemodynamic variables were measured and compared. RESULTS: The entropy following intubation increased significantly in both groups. But entropy changes in group T were greater than those in group P remained below 65. CONCLUSIONS: Our results using the entropy to monitor anesthetic depth during induction and intubation, suggest that thiopental 5 mg/kg is more likely to be associated with lighter planes of anesthesia and consequent risk of arousal reaction following endotracheal intubation than propofol 2 mg/kg.
