Experimental Microangiographic Study in Normal Rabbit Liver.
10.3348/jkrs.1994.30.2.281
- Author:
Byung Soo KIM
;
Jong Yeon PARK
;
Yoon Gyoo KIM
;
Kook Sang HAN
;
Ki Ho MOON
;
Chang Ho CHOI
;
Koon Taek HAN
;
Suck Hong LEE
- Publication Type:Original Article
- MeSH:
Barium;
Catheters;
Diamond;
Formaldehyde;
Heparin;
Liver*;
Polyethylene;
Portal Vein;
Rabbits;
Veins
- From:Journal of the Korean Radiological Society
1994;30(2):281-287
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Microangiography is an experimental radiologic technique for evaluation of the morphology and the function of small vessels. The purpose of this study is to introduce a good microangiographic technique and to present the microangiographic appearance of normal hepatic vascular pattern. MATERIALS AND METHODS: Five white rabbits weighing 2.5-2.9Kg were objected. Polyethylene catheters were inserted in portal vein and then in IVC. Heparin mixed normal saline (2cc/1000cc) was infused through portal vein and blood was drained to IVC. Barium suspension was infused via the catheter placed in portal vein untill the liver surface showed satisfactory finding in barium filling. The liver was removed and this preparation was fixed in 10% formaline for 7 days. After fixation, the liver was sectioned on 1-2mm thickeness. The slices were radiographed on high resolution plate using Faxitron. H-E staining of liver tissue was also done. RESULTS: The microbrium was well distributed in all small vessels without filling defect. And we could find the hexagonal shaped classic liver Iobule, in which the central vein was located at central portion and portal vein at periphery. The enlargement was showed numerous sinusoids, but there was less dye in the central portion of Iobule, but the central vein was well filled by microbarium. The peripheral portion of Iobule was well filled with microbarium. So, we could find diamond shaped liver acinus, in which central vein was located at priperal portion and the center of liver acinus was terminal portal vein that growed out from a small portal space. The three acini made the complex acinus and acinar agglomerate was composed of three or four complex acini. CONCLUSION: It is considered that the liver acinus pattern of Rapparport is more acceptable on microangiography than the classic concept of hepatic Iobule.
