Effectiveness of Toric Orthokeratology in the Treatment of Patients with Combined Myopia and Astigmatism.
10.3341/kjo.2016.30.6.434
- Author:
Byul LYU
1
;
Kyu Yeon HWANG
;
Sun Young KIM
;
Su Young KIM
;
Kyung Sun NA
Author Information
1. Department of Ophthalmology, The Catholic University of Korea College of Medicine, Seoul, Korea. githen@hanmail.net
- Publication Type:Multicenter Study ; Original Article ; Randomized Controlled Trial
- Keywords:
Astigmatism;
Contact lenses;
Myopia;
Orthokeratologic procedures;
Refraction
- MeSH:
Adolescent;
Adult;
Astigmatism/complications/diagnosis/*therapy;
Child;
Cornea/*diagnostic imaging;
Female;
Humans;
Male;
Middle Aged;
Myopia/complications/diagnosis/*therapy;
Orthokeratologic Procedures/*methods;
Slit Lamp Microscopy;
Treatment Outcome;
*Visual Acuity;
Young Adult
- From:Korean Journal of Ophthalmology
2016;30(6):434-442
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The purpose of this multi-institute, single-group clinical trial was to evaluate the effectiveness and safety of toric orthokeratology lenses for the treatment of patients with combined myopia and astigmatism. METHODS: A total of 44 patients were included in this clinical trial. The patients ranged in age from 7 to 49 years, with myopia of -0.75 to -6.0 diopters (D) and astigmatism of 1.25 to 4.0 D. After excluding 21 subjects, 23 subjects (39 eyes) were analyzed after toric orthokeratology lens use. The subjects underwent ophthalmologic examination after 1 day and 1, 2, 3, and 4 weeks of wearing overnight toric orthokeratology lenses. RESULTS: A total of 19 subjects (31 eyes) completed the trial after five subjects (eight eyes) dropped out. In the patients who completed the study by wearing lenses for 4 weeks, the myopic refractive error decreased significantly by 2.60 ± 2.21 D (p < 0.001), from -3.65 ± 1.62 to -1.05 ± 1.64 D. The astigmatic refractive error were also significantly decreased by 0.63 ± 0.98 D (p = 0.001), from 2.07 ± 0.83 to 1.44 ± 0.99 D. The mean uncorrected and corrected visual acuities before wearing the lenses were 2.14 ± 0.80 logarithm of the logMAR (logMAR) and 0.05 ± 0.13 logMAR, respectively, which changed to 0.12 ± 0.30 logarithm of the logMAR (p < 0.001) and 0.01 ± 0.04 logMAR (p = 0.156) after 4 weeks. No serious adverse reactions were reported during the clinical trial. CONCLUSIONS: Our results suggest that toric orthokeratology is an effective and safe treatment for correcting visual acuity in patients with combined myopia and astigmatism.
