A case of primary bilateral adrenal non-Hodgkin's lymphoma.
- Author:
Seo Jong KIM
1
;
Bong Seog KIM
;
Sung Ki PARK
;
Gyo Hyun JIN
;
Kun Ho SO
;
Jeong Seok KOH
;
Sung Kyu LEE
;
Jeong Rye KIM
;
Yong Ho ROH
;
Jong Hoon BYUN
Author Information
1. Department of Internal Medicine, Korea Veterans Hospital, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Adrenal glands;
Lymphoma;
Non - Hodgkin
- MeSH:
3-Iodobenzylguanidine;
Adrenal Glands;
Adrenalectomy;
Adrenocorticotropic Hormone;
Autopsy;
B-Lymphocytes;
Chemistry;
Classification;
Diagnosis, Differential;
Doxorubicin;
Drug Therapy;
Drug Therapy, Combination;
Humans;
Korea;
Lymphoma;
Lymphoma, Non-Hodgkin*;
Magnetic Resonance Imaging;
Middle Aged;
Sepsis;
Vincristine
- From:Korean Journal of Medicine
2000;59(4):423-427
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary adrenal lymphoma is extremely uncommon. The tumor is accidentally discovered by abdominal ultrasonography(USG), computed tomography(CT) or magnetic resonance imaging (MRI) in patients with nonspecific symptoms and diagnosed at operation or autopsy. In this case, a 60-year-old man was admitted for the evaluation of mild left frank discomfort for two months before admission. The abdominal USG was performed and showed the dense masses in both adrenal glands. The laboratory tests including blood count, chemistry and hormonal tests showed the normal levels except for the basal ACTH level of 108 pg/ml(normal range: 9~52 pg/ml). The 123I MIBG scan was normal. The bilateral adrenalectomy was done. The tumor was diagnosed as diffuse large B-cell non-Hodgkin's lymphoma(NHL) according to the Revised European-American lymphoma(REAL) classification. He was treated with the adjuvant combination chemotherapy of CHOP(cyclophosphamide, adriamycin, vincristine and prednisolone) but expired due to sepsis after the second chemotherapy. We describe the first case of primary bilateral adrenal NHL in Korea. Primary adrenal lymphoma should be included in the differential diagnosis of suprarenal mass.
