A case of malignant acanthosis nigricans associated with gastric adenocarcinoma.
- Author:
Jae Kwang SHIM
;
Min Ho KIM
;
Yon Ju HA
;
Sung Gon JUN
;
Tae Kyoung KWON
;
Hee Seung KIM
;
Jung Hoi LEE
;
Yoon Shig YANG
- Publication Type:Original Article
- Keywords:
Stomach neoplasms;
Adenocarcinoma;
Acanthosis nigricans
- MeSH:
Acanthosis Nigricans*;
Adenocarcinoma*;
Aged;
Female;
Gastrointestinal Tract;
Humans;
Hypertrophy;
Lip;
Membranes;
Pigmentation;
Stomach Neoplasms
- From:Korean Journal of Medicine
2000;59(4):438-441
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The new onset of acanthosis nigricans in an adult-especially when the lesions appear on mucosal membranes such as the lips, periocular areas, and anus-may be indicative of an underlying tumor. Adenocarcinoma of the gastrointestinal tract is the most common malignancy-most often cancer of the stomach. A 72 years old female had disseminated, symmetrically distributed, brownish black pigmentation and papillary hypertrophy on the intertriginous and flexural areas for 12 months, and gastric adenocarcinoma was confirmed during the evaluation of internal malignancy. The cutaneous finding of acanthosis nigricans was a significant cutaneous marker of internal malignancy in this case.
