Two cases of CD30+ anaplastic large cell lymphoma.
- Author:
Keun Kyu PARK
1
;
Yong Seok JANG
;
Hong Seok LEE
;
Hong Suk SONG
;
Sang Suk LEE
Author Information
1. Department of Internal Medicine, Keimyung University School of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Lymphoma;
Large - cell;
Ki - 1
- MeSH:
Adult;
Aged;
Biopsy;
Drug Therapy;
Female;
Hepatitis;
Humans;
Lymph Nodes;
Lymphoma;
Lymphoma, Large-Cell, Anaplastic*;
Male;
Splenic Infarction
- From:Korean Journal of Medicine
2000;59(4):442-446
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Two cases of CD30 positive ALCL is presented. A 27 year-old male patient presented with general lymphadenopathies, hepatosplenomegaly, splenic infarction, acute hepatitis, and hemopagocytic syndrome. The other 66 year-old female patient presented with general lymphadenopathies. Biopsy of the lymph node revealed proliferation of anaplastic pleomorphic tumor cells in the sinusoidal pattern. Immunohistochemical study revealed tumor cells were positive for LCA, T cell, and CD 30. All two cases were stage IIIA. Young patient was treat with 8 cycles of ProMACE-CytaBOM chemotherapy, and elderly patient was treated with 8 cycles of CHOP chemotherapy that resulted in complete remission with favorable clinical course.
