A case of bilateral primary adrenal lymphoma.
- Author:
Keun Kyu PARK
1
;
Yong Seok JANG
;
Hong Seok LEE
;
Hong Suk SONG
;
Soong Kook PARK
Author Information
1. Department of Internal Medicine, Keimyung University School of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Adrenal glands;
Lymphoma;
Non - Hodgkin
- MeSH:
Adrenal Glands;
Adrenal Insufficiency;
Aged;
Biopsy;
Diagnosis;
Drug Therapy;
Drug Therapy, Combination;
Follow-Up Studies;
Hemangioma;
Hepatitis C, Chronic;
Humans;
Liver;
Lymphoma*;
Lymphoma, Large B-Cell, Diffuse;
Lymphoma, Non-Hodgkin;
Sepsis;
T-Lymphocytes;
Tomography, X-Ray Computed;
Ultrasonography
- From:Korean Journal of Medicine
2000;59(4):447-451
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary adrenal lymphoma is extremely rare with only 65 cases reported in the worldwide literature until 1998. The presenting symptom may be related to the lymphoma itself or to adrenal insufficiency. Most of the lymphomas were of B cell diffuse large cell type with only two seemed to be T-cell in origin. The therapeutic modalities include surgery, combination chemotherapy, surgery followed by chemotherapy and/or radiation therapy, in addition to corticosteroid replacement. A 65 year old man with chronic hepatitis C and hemangioma of liver presented with general weakness. Abdominal ultrasonography showed bilateral adrenal masses. The adrenal masses were diagnosed as a primary adrenal non-Hodgkin's lymphoma by open biopsy. The histologic findings were consistent with B cell diffuse large cell lymphoma. After three cycles of CHOP chemotherapy, the adrenal mass disappeared on follow up abdominal CT scan, but the patient died 4 months after diagnosis due to sepsis.
