The Cases of Surgical Treatment of Intractable Childhood Epilepsy with Tuberous Sclerosis.
- Author:
Da Eun JUNG
1
;
Jung Chae PARK
;
Hee Jung CHUNG
;
Hoon Chul KANG
;
Heung Dong KIM
;
Yong Soon HWANG
Author Information
1. Epileptic Center, Inje University, College of Medicine, Sang-Gye Paik Hospital, Seoul, Korea. hdkimmd@sanggyepaik.ac.kr
- Publication Type:Case Report
- Keywords:
Tuberous sclerosis;
Epileptic surgery
- MeSH:
Epilepsy*;
Hamartoma;
Humans;
Neurons;
Seizures;
Tuberous Sclerosis*
- From:
Journal of the Korean Child Neurology Society
2002;10(2):314-324
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tuberous sclerosis(TS) is a disorder of aberrant neuronal differentiation and proliferation manifesting as multiple central nervous system(CNS) hamartomas. Seizures in patients with TS are often intractable to anticonvulsant therapy. Although TS shows various lesions including multiple tubers, many patients with well localized epileptic focus to some tubers may have a benefit from epileptic surgery. We experienced three cases who had clinical improvement after epileptic surgery in intractable epilepsy complicated by TS. We report three cases and the brief review of literatures.