Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies.
10.9758/cpn.2016.14.4.391
- Author:
Takashi TOMITA
1
;
Hidekazu GOTO
;
Kenji SUMIYA
;
Tadashi YOSHIDA
;
Katsuya TANAKA
;
Yukinao KOHDA
Author Information
1. Department of Pharmacy, Hospital Bando, Bando, Japan. tatomita@iwate-med.ac.jp
- Publication Type:Case Report
- Keywords:
Adenine;
Leukopenia;
Neutropenia;
Antipsychotic agents;
Lithium carbonate
- MeSH:
Adenine*;
Antipsychotic Agents*;
Humans;
Leukocytes;
Leukopenia*;
Lithium Carbonate*;
Lithium*;
Neutropenia*;
Neutrophils
- From:Clinical Psychopharmacology and Neuroscience
2016;14(4):391-395
- CountryRepublic of Korea
- Language:English
-
Abstract:
Because adenine is effective for managing cases of radiation-induced and drug-induced leukopenia, it may be effective in cases of antipsychotic-induced leukopenia and neutropenia. Here, we report our experience with patients with leukopenia and neutropenia caused by an antipsychotic overdose or discontinuation of lithium carbonate, in whom adenine administration ameliorated the white blood cell and neutrophil counts. The progress of patients suggests that adenine is effective in cases of leukopenia and neutropenia associated with lithium carbonate discontinuation and an antipsychotic overdose.
