Effect of Transdermal scopolamine Patch on Nausea or Vomiting Associated with General Anesthesia.
10.4097/kjae.1993.26.3.434
- Author:
Jeong Sook JANG
1
;
Ji Hyeun OH
;
Jin Gyung JANG
Author Information
1. Department of Anesthesiology, Kang Nam General Hospital, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Postanesthesia;
Nausea;
Vomiting;
Antiemetics;
Transdermal scopolamine patch
- MeSH:
Anesthesia;
Anesthesia, General*;
Antiemetics;
Ear;
Female;
Gynecologic Surgical Procedures;
Humans;
Incidence;
Nausea*;
Oxygen;
Postoperative Nausea and Vomiting;
Scopolamine Hydrobromide*;
Skin;
Thiopental;
Vomiting*
- From:Korean Journal of Anesthesiology
1993;26(3):434-438
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To evaluate the efficacy of transdermal scopolamine patch in reducing nausea and vomiting associated with general anesthesia, we studied 60 healthy women undergoing major gynecologic surgery. The patients were divided into 2 groups. Each group was composed of 30 patients. Group I; not applied a transdermal scopolamine patch. Group II: applied one transdermal scopolamine patch on the skin behind her ear at the night before surgery. Anesthesia was induced by thiopental sodium(5 mg/kg) and succinylcholine(1.5 mg/kg) and maintained with fentanyl(3-6 ug/kg), enflurane(0.5-1.5 vol%) and nitrous oxide(50 vo1%) in oxygen. A comparison with Group I and Group II indicated that the transdermal scopolamine patch reduced the incidence of postoperative nausea or vomiting associated with general anesthesia significantly(Group I; 36.67%, Group II; 13.33%, p<0.05).
