A Case of Chronic Lymphoplasmacellular Osteomyelitiswith Autoimmune Hepatitis/Primary SclerosingCholangitis Overlap Syndrome in a Child.
- Author:
Ji Hyuk LEE
1
;
Hyun Young LEE
;
Jin Kyu KIM
;
Jee Hyun LEE
;
Yon Ho CHOE
Author Information
1. Department of Pediatrics, Samsung Medical Center, Sungkyunkwan UniversitySchool of Medicine, Seoul, Korea. cyh@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Overlap syndrome;
Autoimmune hepatitis;
Primary sclerosing cholangitis;
Chronic lymphoplasmacellular osteomyelitis
- MeSH:
Autoimmune Diseases;
Child*;
Cholangitis, Sclerosing;
Colitis, Ulcerative;
Female;
Hepatitis, Autoimmune;
Humans;
Inflammatory Bowel Diseases;
Liver Cirrhosis, Biliary;
Osteomyelitis
- From:Korean Journal of Pediatric Gastroenterology and Nutrition
2007;10(1):91-97
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The Overlap syndrome is characterized by a combination of the major hepatobiliary autoimmune diseases such as autoimmune hepatitis, primary biliary cirrhosis and primary sclerosing cholangitis. It is frequently accompanied by inflammatory bowel disease. Chronic lymphoplasmacellular osteomyelitis is characterized by recurrent episodes of bacterial osteomyelitis and is associated with autoimmune diseases (especially inflammatory bowel disease). We report the case of a girl who was diagnosed with ulcerative colitis and autoimmune hepatitis at 4 years of age and with the overlap syndrome with primary sclerosing cholangitis at 6 years. At 9 years, she was diagnosed with chronic lymphoplasmacellular osteomyelitis.
